解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The anuran amphibian Xenopus laevis can regenerate its limbs for a limited time during the larval stage, while limbs are still developing. Using this regeneration model, we evaluated the proximo-distal blastema cell identity when endogenous retinoids were increased by CYP26 inhibition or when RAR-specific agonists alt...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01886
更新日期:2013-01-01 00:00:00
abstract::Studies reveal that there exists much interaction and communication between bacterial cells, with parts of these social behaviors depending on cell-cell contacts. The cell-cell contact has proved to be crucial for determining various biochemical processes. However, for cell culture with relatively low cell concentrati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01993
更新日期:2013-01-01 00:00:00
abstract::The patterns of life exhibited by large populations have been described and modeled both as a basic science exercise and for a range of applied goals such as reducing automotive congestion, improving disaster response, and even predicting the location of individuals. However, these studies have had limited access to c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02625
更新日期:2013-01-01 00:00:00
abstract::Large-offset oceanic detachment faults are a characteristic of slow- and ultraslow-spreading ridges, leading to the formation of oceanic core complexes (OCCs) that expose upper mantle and lower crustal rocks on the seafloor. The lithospheric extension accommodated by these structures is now recognized as a fundamental...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02336
更新日期:2013-01-01 00:00:00
abstract::Cyclamen persicum (cyclamen) is a commercially valuable, winter-blooming perennial plant. We cloned two cyclamen orthologues of AGAMOUS (AG), CpAG1 and CpAG2, which are mainly expressed in the stamen and carpel, respectively. Cyclamen flowers have 5 petals, but expression of a chimeric repressor of CpAG1 (CpAG1-SRDX) ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02641
更新日期:2013-01-01 00:00:00
abstract::A series of edge-selectively halogenated (X = Cl, Br, I) graphene nanoplatelets (XGnPs = ClGnP, BrGnP, IGnP) were prepared simply by ball-milling graphite in the presence of Cl2, Br2 and I2, respectively. High BET surface areas of 471, 579 and 662 m(2)/g were observed for ClGnP, BrGnP and IGnP, respectively, indicatin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01810
更新日期:2013-01-01 00:00:00
abstract::Metals can transmit light by tunnelling when they possess skin-depth thickness. Tunnelling can be resonantly enhanced if resonators are added to each side of a metal film, such as additional dielectric layers or periodic structures on a metal surface. Here we show that, even with no additional resonators, tunnelling r...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02423
更新日期:2013-01-01 00:00:00
abstract::A hematite photoanode showing a stable, record-breaking performance of 4.32 mA/cm² photoelectrochemical water oxidation current at 1.23 V vs. RHE under simulated 1-sun (100 mW/cm²) irradiation is reported. This photocurrent corresponds to ca. 34% of the maximum theoretical limit expected for hematite with a band gap o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02681
更新日期:2013-01-01 00:00:00
abstract::The characterization of fully-defined in vitro hepatic culture systems requires testing of functional and morphological variables to obtain the optimal trophic support, particularly for cell therapeutics including bioartificial liver systems (BALs). Using serum-free fully-defined culture medium formulations, we measur...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02735
更新日期:2013-01-01 00:00:00
abstract::We study the S = 1/2 Kondo lattice model which is widely used to describe heavy fermion behavior. In conventional treatments of the model the Kondo interaction is decoupled in favour of a hybridization of conduction and localized f electrons. However, such an approximation breaks the local gauge symmetry and implicate...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02691
更新日期:2013-01-01 00:00:00
abstract::The evolution of cooperation requires some mechanism that reduces the risk of exploitation for cooperative individuals. Recent studies have shown that men with wide faces are anti-social, and they are perceived that way by others. This suggests that people could use facial width to identify anti-social men and thus li...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01047
更新日期:2013-01-01 00:00:00
abstract::Pitch is a complex hearing phenomenon that results from elicited and self-generated cochlear vibrations. Read-off vibrational information is relayed higher up the auditory pathway, where it is then condensed into pitch sensation. How this can adequately be described in terms of physics has largely remained an open que...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02676
更新日期:2013-01-01 00:00:00
abstract::Radionuclide concentrations in environmental samples such as surface soils, plants and water were evaluated by high purity germanium detector measurements. The contribution rate of short half-life radionuclides such as (132)I to the exposure dose to residents was discussed from the measured values. The highest values ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02283
更新日期:2013-01-01 00:00:00
abstract::Melanoma patients with BRAF mutations respond to treatment with vemurafenib, thus creating a need for accurate testing of BRAF mutation status. We carried out a blinded study to evaluate various BRAF mutation testing methodologies in the clinical setting. Formalin-fixed, paraffin-embedded melanoma samples were macrodi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01659
更新日期:2013-01-01 00:00:00
abstract::Particles manipulation with optical forces is known as optical tweezing. While tweezing in free space with laser beams was established in the 1980s, integrating the optical tweezers on a chip is a challenging task. Recent experiments with plasmonic nanoantennas, microring resonators, and photonic crystal nanocavities ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02290
更新日期:2013-01-01 00:00:00
abstract::With modern scanning probe microscopes, it is possible to manipulate surface structures even at the atomic level. However, manipulation of nanoscale objects such as clusters is often more relevant and also more challenging due to the complicated interactions between the surface, cluster and apparatus. We demonstrate t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01270
更新日期:2013-01-01 00:00:00
abstract::Computational studies considering both thermodynamic and kinetic aspects revealed that graphyne, a carbon material that has recently been of increasing interest, favours unprecedented homogeneous "in-plane" addition reactions. The addition of dichlorocarbene to the C(sp)-C(sp) bond, a site with outstanding regioselect...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01271
更新日期:2013-01-01 00:00:00
abstract::Oxide heterointerfaces are ideal for investigating strong correlation effects to electron transport, relevant for oxide-electronics. Using hot-electrons, we probe electron transport perpendicular to the La₀.₇Sr₀.₃MnO₃ (LSMO)- Nb-doped SrTiO₃ (Nb:STO) interface and find the characteristic hot-electron attenuation lengt...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01274
更新日期:2013-01-01 00:00:00
abstract::Saturn rings are most beautiful and dynamic places in the solar system, consisting of ice particles in a constant battle between the gravitational forces of Saturn and its many moons. Fan, spiral, propellers, moonlets and streamer-channels observed by CASSINI in the F-ring have been attributed to encounters by Prometh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01276
更新日期:2013-01-01 00:00:00
abstract::Breast cancer transcriptome acquires a myriad of regulation changes, and splicing is critical for the cell to "tailor-make" specific functional transcripts. We systematically revealed splicing signatures of the three most common types of breast tumors using RNA sequencing: TNBC, non-TNBC and HER2-positive breast cance...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01689
更新日期:2013-01-01 00:00:00
abstract::The high theoretical capacity and low discharge potential of silicon have attracted much attention on Si-based anodes. Herein, hollow porous SiO2 nanocubes have been prepared via a two-step hard-template process and evaluated as electrode materials for lithium-ion batteries. The hollow porous SiO2 nanocubes exhibited ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01568
更新日期:2013-01-01 00:00:00
abstract::Do scientists follow hot topics in their scientific investigations? In this paper, by performing analysis to papers published in the American Physical Society (APS) Physical Review journals, it is found that papers are more likely to be attracted by hot fields, where the hotness of a field is measured by the number of...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02207
更新日期:2013-01-01 00:00:00
abstract::Several studies provide evidence of a link between vector-borne disease outbreaks and El Niño driven climate anomalies. Less investigated are the effects of the North Atlantic Oscillation (NAO). Here, we test its impact on outbreak occurrences of 13 infectious diseases over Europe during the last fifty years, controll...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01774
更新日期:2013-01-01 00:00:00
abstract::Here we show that electrical tuning of the sensitivity of chemitransistor sensors, namely field-effect-transistors (FETs) exploiting nano/mesostructured sensing materials, can be used to effectively address two chief problems of state-of-the-art gas sensors, specifically fabrication reliability and degradation by agin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01161
更新日期:2013-01-01 00:00:00
abstract::Generally, the length of the oxide nanowires grown by vapor phase transport is limited by the degradation of the source materials. Furthermore, the source material is used once for the nanowires growth. By exploiting the Si-Zn phase diagram, we have developed a simple methodology for the non-catalytic growth of ultral...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01172
更新日期:2013-01-01 00:00:00
abstract::Artificially structured coatings are widely employed to minimize materials deterioration and corrosion, the annual direct cost of which is over 3% of the gross domestic product (GDP) for industrial countries. Manufacturing higher performance anticorrosive coatings is one of the most efficient approaches to reduce this...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01177
更新日期:2013-01-01 00:00:00
abstract::Environmental context strongly affects many host-pathogen interactions, but the underlying causes of these effects at the individual level are usually poorly understood. The amphibian chytrid fungus has caused amphibian population declines and extinctions in many parts of the world. Many amphibian species that have de...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01515
更新日期:2013-01-01 00:00:00
abstract::Human Influenza A virus undergoes recurrent changes in the hemagglutinin (HA) surface protein, primarily involved in the human antibody recognition. Relevant antigenic changes, enabling the virus to evade host immune response, have been recognized to occur in parallel to multiple mutations at antigenic sites in HA. Ye...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02705
更新日期:2013-01-01 00:00:00
abstract::We study stochastic particle systems made up of heterogeneous units. We introduce a general framework suitable to analytically study this kind of systems and apply it to two particular models of interest in economy and epidemiology. We show that particle heterogeneity can enhance or decrease the size of the collective...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01189
更新日期:2013-01-01 00:00:00
abstract::Studies of past human-landscape interactions rely upon the integration of archaeological, biological and geological information within their geographical context. However, detecting the often ephemeral traces of human activities at a landscape scale remains difficult with conventional archaeological field survey. Geop...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01517
更新日期:2013-01-01 00:00:00
abstract::We introduce a setup which realises a tunable engineered environment for experiments in circuit quantum electrodynamics. We illustrate this concept with the specific example of a quantum bit, qubit, in a high-quality-factor cavity which is capacitively coupled to another cavity including a resistor. The temperature of...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01987
更新日期:2013-01-01 00:00:00
abstract::Ischemia-reperfusion (I/R) injury model has been widely applied to the study of microcirculation disturbance. In this work, we used laser oblique scanning optical microscopy (LOSOM) to observe the microcirculation system in the mesentery of rat model. Utilizing a localized point-scanning detection scheme, high-contras...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01762
更新日期:2013-01-01 00:00:00
abstract::Two dimensional (2D) materials with a monolayer of atoms represent an ultimate control of material dimension in the vertical direction. Molybdenum sulfide (MoS2) monolayers, with a direct bandgap of 1.8 eV, offer an unprecedented prospect of miniaturizing semiconductor science and technology down to a truly atomic sca...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01866
更新日期:2013-01-01 00:00:00
abstract::The integral membrane-bound Nrf1 transcription factor fulfils important functions in maintaining cellular homeostasis and organ integrity, but how it is controlled vectorially is unknown. Herein, creative use of Gal4-based reporter assays with protease protection assays (GRAPPA), and double fluorescence protease prote...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02006
更新日期:2013-01-01 00:00:00
abstract::Endocannabinoids are small signaling lipids, with 2-arachidonoylglycerol (2-AG) implicated in modulating axonal growth and synaptic plasticity. The concept of short-range extracellular signaling by endocannabinoids is supported by the lack of trans-synaptic 2-AG signaling in mice lacking sn-1-diacylglycerol lipases (D...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02093
更新日期:2013-01-01 00:00:00
abstract::Single epitaxially-grown semiconductor quantum dots have great potential as single photon sources for photonic quantum technologies, though in practice devices often exhibit nonideal behavior. Here, we demonstrate that amplitude modulation can improve the performance of quantum-dot-based sources. Starting with a brigh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01397
更新日期:2013-01-01 00:00:00
abstract::This work reports a facile method for preparing the new photoactive In(2)O(3) films as well as their implementation in photoelectrochemical (PEC) application. We firstly investigated the relationship between oxygen vacancies (V(O)) and PEC performance and revealed a rule between them. We found that the optimized In(2)...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01021
更新日期:2013-01-01 00:00:00
abstract::Here we present an ultraviolet responsive inorganic-organic hybrid solar cell based on titania/poly(3-hexylthiophene) (TiO(2)/P3HT) heterojuction. In this solar cell, TiO(2) is an ultraviolet light absorber and electronic conductor, P3HT is a hole conductor, the light-to-electrical conversion is realized by the cooper...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01283
更新日期:2013-01-01 00:00:00
abstract::Increased connectivity with the mainland has led to the arrival of many invasive species to the Galápagos Islands, including novel pathogens, threatening the archipelago's unique fauna. Here we consider the potential role of the mosquito Aedes taeniorhynchus in maintaining the flavivirus West Nile virus [WNV] should i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01519
更新日期:2013-01-01 00:00:00
abstract::The high manufacturing cost for metallic glasses hampers actual commercial applications of this class of fascinating materials. In this letter, the effect of oxygen impurity on the glass forming ability and tensile properties of Zr-BMG composites were studied. Our results have demonstrated that oxygen was absorbed and...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02097
更新日期:2013-01-01 00:00:00